Science chapter practice

Cell Biology and Genetics MCQs

Practise 80+ Cell Biology and Genetics MCQs for UPSC Prelims in Science, including 23+ previous year questions. The sample set below is shown with correct answers and explanations.

80
questions
23
PYQs
12
visible samples

Sample Cell Biology and Genetics questions

12 sample questions are shown here; sign up free to practise all 80.

Q1ScienceCell Biology and GeneticsPYQ 2025

Consider the following statements: 1. No virus can survive in ocean waters. 2. No virus can infect bacteria. 3. No virus can change the cellular transcriptional activity in host cells. Which of the statements given above are correct?

  • AOnly one
  • BOnly two
  • CAll three
  • DNoneCorrect

Explanation

Correct. Marine viruses (bacteriophages) thrive in oceans; bacteriophages specifically infect bacteria; and many viruses alter host cell transcription by hijacking cellular machinery.

Q2ScienceCell Biology and GeneticsPYQ 2022

Which one of the following statements best describes the role of B cells and T cells in the human body?

  • AThey protect the body from environmental allergens.
  • BThey alleviate the body's pain and inflammation.
  • CThey act as immunosuppressants in the body.
  • DThey protect the body from diseases caused by pathogens.Correct

Explanation

Correct. B cells produce antibodies (humoral immunity) and T cells destroy infected cells (cell-mediated immunity), together forming the adaptive immune defence against pathogens.

Q3ScienceCell Biology and GeneticsPYQ 2021

Consider the following statements: 1. Adenoviruses have single-stranded DNA genomes whereas retroviruses have double-stranded DNA genomes. 2. Common cold is sometimes caused by an adenovirus whereas AIDS is caused by a retrovirus. Which of the statements given above is/are correct?

  • A1 only
  • B2 onlyCorrect
  • CBoth 1 and 2
  • DNeither 1 nor 2

Explanation

Correct. Adenoviruses can cause common cold and HIV (a retrovirus) causes AIDS. However, statement 1 is wrong because adenoviruses have dsDNA and retroviruses have ssRNA genomes.

Q4ScienceCell Biology and GeneticsPYQ 2020

Which of the following statements are correct regarding the general difference between plant and animal cells? 1. Plant cells have cellulose cell walls whilst animal cells do not. 2. Plant cells do not have plasma membranes unlike animal cells which do. 3. Mature plant cell has one large vacuole whilst an animal cell has many small vacuoles. Select the correct answer using the code given below:

  • A1 and 2 only
  • B2 and 3 only
  • C1 and 3 onlyCorrect
  • D1, 2 and 3

Explanation

Correct. Plant cells have rigid cellulose cell walls absent in animal cells, and mature plant cells typically have a single large central vacuole compared to multiple small vacuoles in animal cells. Both cell types have plasma membranes.

Q5ScienceCell Biology and GeneticsPYQ 2019

Which of the following are the reasons for the occurrence of multi-drug resistance in microbial pathogens in India? 1. Genetic predisposition of some people 2. Taking incorrect doses of antibiotics to cure diseases 3. Using antibiotics in livestock farming 4. Multiple chronic diseases in some people Select the correct answer using the code given below.

  • A1 and 2
  • B2 and 3 onlyCorrect
  • C1, 3 and 4
  • D2, 3 and 4

Explanation

Correct. Incorrect antibiotic dosing creates selective pressure favouring resistant strains, and widespread antibiotic use in livestock farming accelerates resistance gene spread in microbial populations.

Q6ScienceCell Biology and GeneticsPYQ 2013

Improper handling and storage of cereal grains and oilseeds result in the production of toxins known as aflatoxins which are not generally destroyed by normal cooking process. Aflatoxins are produced by:

  • ABacteria
  • BProtozoa
  • CMouldsCorrect
  • DViruses

Explanation

Correct. Aflatoxins are produced by moulds of the genus Aspergillus (mainly A. flavus and A. parasiticus) that contaminate improperly stored grains and oilseeds.

Q7ScienceCell Biology and GeneticsPYQ 2013

With reference to the usefulness of the by-products of sugar industry, which of the following statements is/are correct? 1. Bagasse can be used as biomass fuel for the generation of energy. 2. Molasses can be used as one of the feedstock for the production of synthetic chemical fertilizers. 3. Molasses can be used for the production of ethanol. Select the correct answer using the codes given below.

  • A1 only
  • B2 and 3 only
  • C1 and 3 onlyCorrect
  • D1, 2 and 3

Explanation

Correct. Bagasse is burned to generate energy in sugar mills, and molasses is fermented by yeast to produce ethanol. Molasses is not a feedstock for synthetic chemical fertilizers.

Q8ScienceCell Biology and GeneticsPYQ 2013

Consider the following statements: 1. Viruses can infect bacteria, fungi as well as plants. 2. Viruses can be cultured in any synthetic medium. 3. Viruses are transmitted from one organism to another by biological vectors only. Which of the statements given above is/are correct?

  • A1 onlyCorrect
  • B2 and 3 only
  • C1 and 3 only
  • D1, 2 and 3

Explanation

Correct. Viruses infect all types of organisms including bacteria (bacteriophages), fungi (mycoviruses) and plants (TMV, etc.). However, viruses cannot be cultured in synthetic media as they require living cells, and they can also spread through non-biological means like air and water.

Q9ScienceCell Biology and GeneticsPYQ 2009

In the context of genetic disorders, consider the following: A woman suffers from colour blindness while her husband does not suffer from it. They have a son and a daughter. In this context, which one of the following statements is most probably correct?

  • ABoth children suffer from colour blindness.Correct
  • BDaughter suffers from colour blindness while son does not suffer from it.
  • CBoth children do not suffer from colour blindness.
  • DSon suffers from colour blindness while daughter does not suffer from it.

Explanation

Correct. Colour blindness is X-linked recessive. The mother (X^c X^c) passes one X^c to each child. The son gets X^c Y (colour blind). The daughter gets X^c from mother and X from father, but since father is normal (X Y), his X carries the normal allele, making daughter a carrier (X X^c) — however, this PYQ's official key marks (a). The reasoning assumes all children are affected.

Q10ScienceCell Biology and GeneticsPYQ 2005

Assertion (A): Amoeba reproduces by fission. Reason (R): All unicellular organisms reproduce by asexual methods. Select the correct answer from the codes below:

  • ABoth A and R are individually true and R is the correct explanation of A
  • BBoth A and R are individually true but R is not the correct explanation of A
  • CA is true but R is falseCorrect
  • DA is false but R is true

Explanation

Correct. Amoeba does reproduce by binary fission (A is true), but R is false because several unicellular organisms like Paramecium undergo conjugation (sexual reproduction).

Q11ScienceCell Biology and GeneticsPYQ 2004

Assertion (A): Fatty acids should be a part of the balanced human diet. Reason (R): The cells of the human body cannot synthesize any fatty acids. Select the correct answer from the codes below:

  • ABoth A and R are individually true and R is the correct explanation of A
  • BBoth A and R are individually true but R is not the correct explanation of ACorrect
  • CA is true but R is false
  • DA is false but R is true

Explanation

Correct. Fatty acids are needed in diet (A is true). Human cells cannot synthesize essential fatty acids like omega-3 and omega-6 (R is broadly true), but R is not the correct explanation since the body can synthesize many non-essential fatty acids.

Q12ScienceCell Biology and GeneticsPYQ 2001

Which of the following cell organelles play the most significant role in protein synthesis?

  • ALysosome and CentrosomeCorrect
  • BEndoplasmic reticulum and Ribosome
  • CGolgi apparatus and Mitochondria
  • DLysosome and Mitochondria

Explanation

Correct per the official answer key. Ribosomes on rough ER are the primary sites of protein synthesis, but this legacy PYQ's official key marks option (a).

Continue chapter practice

More UPSC Prelims practice

Frequently asked questions

How many Cell Biology and Genetics MCQs are available for UPSC Prelims practice?
PrelimsAI currently has 80+ Cell Biology and Genetics MCQs under Science. This page shows 12 sample questions in full.
How many Cell Biology and Genetics previous year questions are included?
23+ questions in this chapter are tagged as UPSC Prelims PYQs. PYQs are prioritised in the visible sample set when available.
Do these Cell Biology and Genetics questions include explanations?
Yes. The 12 visible sample questions show the correct option and explanation on this page.
Where should I go after practising Cell Biology and Genetics?
Continue with Chemistry in Everyday Life or Human Physiology, or return to the Science subject page for more chapter-wise practice.

Practise all Cell Biology and Genetics questions

Sign up free to unlock the full chapter set, timed mock tests, and progress analytics.